Bristol Myers Squibb is committed to helping appropriate patients get access to our
medications by providing access and reimbursement support services.

This information is intended for U.S. healthcare professionals and/or healthcare professionals involved in healthcare reimbursement.

Billing and
Diagnosis Codes

The accurate completion of reimbursement- or coverage-related documentation is the responsibility of the healthcare provider and patient. Bristol Myers Squibb and its agents make no guarantee regarding reimbursement for any service or item.

Reimbursement and Coding Guide for REBLOZYL
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Type a keyword to find a specific HCPCS, CPT, NDC, or ICD-10 code
Healthcare Common Procedure Coding System (HCPCS) Codes1 Issued by CMS
J0896

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Injection, luspatercept-aamt, 0.25 mg

Revenue Codes (for Hospital Use)2
0636

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Drugs requiring detailed coding

0250

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Pharmacy (General)

0331

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Chemotherapy administration, injected

Current Procedural Terminology (CPT)3†
96372

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Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); subcutaneous or intramuscular

96401 (for potential use only in MDS)

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Chemotherapy administration, subcutaneous or intramuscular; non-hormonal anti-neoplastic

National Drug Codes (NDC)4 Issued by the FDA Note: Payers require the submission of the 11-digit NDC on healthcare claim forms. Please use the 11-digit codes shown here.
59572-0711-01

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25 mg lyophilized powder in a single-dose vial for reconstitution

59572-0775-01

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75 mg lyophilized powder in a single-dose vial for reconstitution

International Classification of Diseases, Tenth Revision, Clinical Modification Diagnosis Codes (ICD-10-CM)5

Beta Thalassemia
D56.1

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  • Beta thalassemia major
  • Cooley’s anemia
  • Homozygous beta thalassemia
  • Severe beta thalassemia
  • Thalassemia intermedia
  • Thalassemia major
D56.5

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Hemoglobin E-beta thalassemia

Myelodysplastic Syndromes
D46.0

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Refractory anemia without ring sideroblasts, so stated

D46.1

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Refractory anemia with ring sideroblasts

D46.A

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Refractory cytopenia with multilineage dysplasia

D46.B

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Refractory cytopenia with multilineage dysplasia and ring sideroblasts

D46.4

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Refractory anemia, unspecified

D46.Z

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Other myelodysplastic syndromes

D46.9

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Myelodysplastic syndrome, unspecified

REBLOZYL may be purchased through the distributors listed below.

Physician Offices

Authorized Distributor Phone Orders Fax Orders and Website
Cardinal Health Specialty
Pharmaceutical Distribution
1-877-453-3972 https://specialtyonline.cardinalhealth.com
CuraScript Specialty Distribution 1-877-599-7748 https://www.curascriptsd.com
McKesson Specialty Health 1-800-482-6700 https://mscs.mckesson.com
Morris & Dickson Specialty 1-800-710-6100 Fax:
1-318-524-3096
https://www.mdspecialtydist.com
Oncology Supply 1-800-633-7555 https://www.oncologysupply.com

For offices that prefer to use the services of a specialty pharmacy, specialty pharmacies can obtain REBLOZYL from the distributors listed above.

Hospitals and Infusion Centers

Authorized Distributor Phone Orders Fax Orders and Website
ASD Healthcare 1-800-746-6273 Fax:
1-800-547-9413
https://www.asdhealthcare.com
Cardinal Health Specialty
Pharmaceutical Distribution
1-866-677-4844 Fax:
1-614-553-6301
https://orderexpress.cardinalhealth.com
DMS Pharmaceutical Group, Inc. 1-877-788-1100 Fax:
1-847-518-1105
www.dmspharma.com
McKesson
Plasma and Biologics
1-877-625-2566 Fax:
1-888-752-7626
https://connect.mckesson.com
Morris & Dickson Specialty 1-800-710-6100 Fax: 1-318-524-3096
https://www.mdspecialtydist.com

Puerto Rico Hospitals and Clinics

Authorized Distributor Phone Orders Fax Orders and Website
Cardinal Puerto Rico (Borschow) 1-787-625-4200 https://orderexpress.cardinalhealth.com
Cesar Castillo, Inc. 1-787-641-5242 (Hospitals)
1-787-641-5082 (Specialty Pharmacies)
Fax:
1-787-999-1614
https://www.facilfarmaciacci.com
AmerisourceBergen Puerto Rico 1-844-222-2273 https://abcorder.amerisourcebergen.com

Above information is accurate as of 08/23.

The REBLOZYL distribution program includes extended payment terms to Bristol Myers Squibb authorized REBLOZYL distributors. Healthcare providers and institutions should contact their REBLOZYL distributor to understand specific payment terms that may be available to them from their distributor.

Please see U.S. Full Prescribing Information for REBLOZYL.

FDA Approval Letters as Posted by the FDA:

For the treatment of anemia in adult patients with beta thalassemia who require regular red blood cell (RBC) transfusions.
View Letter

For the treatment of anemia failing an erythropoiesis stimulating agent and requiring 2 or more red blood cell units over 8 weeks in adult patients with very low- to intermediate-risk myelodysplastic syndromes with ring sideroblasts (MDS-RS) or with myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T).
View Letter

For the treatment of anemia without previous erythropoiesis stimulating agent use (ESA-naïve) in adult patients with very low- to intermediate-risk myelodysplastic syndromes (MDS) who may require regular red blood cell (RBC) transfusions.
View Letter

Please see U.S. Full Prescribing Information for REBLOZYL.

Coding for REBLOZYL is dependent on the insurer and the care setting in which the drug will be administered. Oncology practices need to make coding decisions based on the diagnosis and treatment of each patient and the specific insurer requirements.

Please see U.S. Full Prescribing Information for REBLOZYL.

*Healthcare providers should code healthcare claims based upon the service that is rendered, the patient's medical record, the coding requirements of each health insurer, and best coding practices. Coding guidance provided under this heading does not provide a guarantee of reimbursement and should be considered together with all applicable coding guidance and standards. All of the coding information presented by this website is applicable to outpatient procedures only.

CPT codes and descriptions only are ©2019 by American Medical Association (AMA). All rights reserved. The AMA assumes no liability for data contained or not contained herein. CPT is a registered trademark of the American Medical Association.

References:

  1. Centers for Medicare & Medicaid Services. Centers for Medicare & Medicaid Services (CMS) Healthcare Common Procedure Coding System (HCPCS) Application Summaries and Coding Decisions: First Quarter, 2020 Coding Cycle for Drug and Biological Products. https://www.cms.gov/files/document/2020-hcpcs-application-summary-quarter-1-2020-drugs-and-biologicals-updated-04142020.pdf. Accessed July 18, 2023.
  2. National Uniform Billing Committee (NUBC). Official UB-04 Data Specifications Manual 2020. American Hospital Association; 2019. Accessed July 18, 2023.
  3. American Medical Association. CPT Professional 2020. Professional ed. Chicago, IL: American Medical Association; 2019. Accessed July 18, 2023.
  4. REBLOZYL [package insert]. Princeton, NJ: Bristol-Myers Squibb Company.
  5. Centers for Medicare & Medicaid Services. ICD-10-CM tabular list of diseases and injuries. https://www.cms.gov/Medicare/Coding/ICD10/2023-ICD-10-CM. Accessed July 18, 2023.

The accurate completion of reimbursement- or coverage-related documentation is the responsibility of the healthcare provider and patient. Bristol Myers Squibb and its agents make no guarantee regarding reimbursement for any service or item.

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Use of the information on this site is subject to the terms of our Legal Notice and Privacy Statement. The coding, coverage, and payment information contained within this website is current as of 04/22.

2007-US-2100436 04/22